5 Doctor-Recommended Products for Dark Spots: A Deep Dive

Dark spots—those stubborn patches left behind by acne, sun exposure, or hormonal shifts—can be a real challenge for anyone aiming for an even, glowing complexion. Whether you’re dealing with post-inflammatory hyperpigmentation, melasma, or age spots, dermatologists agree: the right science-backed products can make a world of difference. If you’re searching for effective solutions, here’s a detailed look at five standout products from DelMeds, each designed to tackle pigmentation at its source. Plus, you’ll find internal links to related resources and tips for building a complete dark spot-fighting routine.
Why Do Dark Spots Appear?
Before diving into product recommendations, it’s important to understand why dark spots form. The skin produces melanin to protect itself from damage, but sometimes this process goes into overdrive, often triggered by inflammation (like acne), UV exposure, or hormonal changes. The result? Patches of excess pigment can linger for months or even years.

1. Regium Epiligium HQ Gel
Key Ingredients: Hydroquinone, Tretinoin, Mometasone
This gel is a dermatologist's favourite for stubborn pigmentation, especially melasma and post-inflammatory hyperpigmentation. Hydroquinone is the gold standard for skin lightening, working by inhibiting melanin production at the cellular level. Tretinoin, a retinoid, accelerates cell turnover, helping to shed pigmented cells faster and reveal fresher skin underneath. Mometasone, a corticosteroid, soothes inflammation, reducing the risk of irritation that often comes with strong actives.
How to Use:
Apply a thin layer to clean, dry skin—usually at night. Use only as directed by your dermatologist, as this is a prescription-strength product. Always follow up with sunscreen during the day, as hydroquinone and tretinoin can make skin more sensitive to UV damage.
What Users Say:
People report visible fading of dark spots and smoother skin texture within weeks. The lightweight formula absorbs quickly, making it easy to layer under other products or makeup.
Pro Tip:
Introduce this gel gradually into your routine to minimise irritation. Never use it on broken or irritated skin.
2. Niashine Brightening Serum
Key Ingredient: Niacinamide
If you’re looking for a gentle yet effective solution, Niashine Brightening Serum is a top pick. Niacinamide (Vitamin B3) is celebrated for its ability to fade dark spots, even skin tone, and strengthen the skin barrier—all without causing irritation, making it ideal for sensitive skin. This serum also contains Vitamin C and botanical extracts, providing extra antioxidant protection and hydration.
How to Use:
Apply a few drops to cleansed skin, morning and evening. Massage gently until fully absorbed, then follow with moisturiser and sunscreen.
What Users Say:
Regular use leads to a brighter, more luminous complexion and a noticeable reduction in dark spots. The lightweight, non-greasy formula makes it suitable for all skin types, including oily and sensitive skin.
Shop Niashine Brightening Serum
3. Kozilite H Skin Lightening Cream
Key Ingredients: Kojic Acid, Arbutin, Vitamin C, Hydroquinone, Glycolic Acid
Kozilite H is a multi-ingredient powerhouse targeting pigmentation from several angles. Kojic acid and arbutin inhibit melanin formation, while hydroquinone and glycolic acid accelerate skin renewal and lighten existing spots. Vitamin C adds antioxidant protection, helping to brighten skin and prevent new spots from forming.
How to Use:
Apply a small amount to affected areas after cleansing, preferably at night. Always use sunscreen during the day, as these actives can increase sun sensitivity.
What Users Say:
Users notice faster fading of blemishes, freckles, and age spots, with skin looking more even and radiant over time. The cream also helps with chloasma and other persistent pigmentation issues.
4. Demelan Cream
Key Ingredients: Glycolic Acid, Arbutin, Kojic Acid
Demelan Cream is a dermatologist-formulated solution for dark spots, melasma, and uneven skin tone. Glycolic acid gently exfoliates, removing dead skin cells and boosting the penetration of other actives. Arbutin and kojic acid work together to inhibit melanin production, visibly brightening dull skin and fading acne scars and sun spots.
How to Use:
Apply a small amount to the affected area after cleansing, preferably at night. Use regularly for best results, and always follow with sunscreen during the day.
What Users Say:
People see a reduction in acne marks, facial discolouration, and even pregnancy-related pigmentation. The cream is suitable for all skin types and leaves skin looking clearer and more radiant.
5. Fixderma Skarfix-TX Cream
Key Ingredients: Tranexamic Acid, Kojic Acid, Niacinamide, Alpha Arbutin, Vitamin E
Skarfix-TX Cream is a modern approach to stubborn pigmentation, using tranexamic acid—a rising star in dermatology—to inhibit melanin transfer and calm inflammation. Kojic acid and alpha arbutin amplify the brightening effect, while niacinamide and vitamin E support skin barrier repair and hydration.
Tranexamic acid is particularly effective for melasma, post-inflammatory hyperpigmentation, and persistent dark spots. It works by blocking the enzyme tyrosinase, which is crucial for melanin production, and by calming overstimulated melanocytes.
How to Use:
Apply a thin layer to affected areas after cleansing, once or twice daily. Always patch test before first use and discontinue if irritation occurs. Sunscreen is a must when using this product.
What Users Say:
Users report a visible reduction in melasma, PIE (post-inflammatory erythema), and PIH (post-inflammatory hyperpigmentation). The cream is also praised for its soothing, non-greasy feel and ability to improve overall skin tone.
How to Maximise Results: Tips for Fading Dark Spots
- Consistency is key: Use your chosen product as directed, and don’t skip days.
- Always wear sunscreen: UV exposure can worsen pigmentation and undo your progress.
- Don’t mix too many actives: Layering multiple strong ingredients can irritate your skin and slow results.
- Patch test new products, especially if you have sensitive skin or a history of reactions.
- Be patient: Most treatments take several weeks to show visible improvement.
- Final Thoughts
Not all dark spots are created equal, so finding the right product depends on your skin’s needs and sensitivities. Whether you prefer the gentle approach of niacinamide or the dermatologist-strength combination of hydroquinone and tretinoin, there’s a solution out there for you. The key is to be patient, consistent, and always prioritise sun protection.
Real care. Real results. Only at DelMeds.
DISCLAIMER : This website provides general information for educational purposes only and should not be considered a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare professional with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay seeking it because of information you've read on this website. Your health is important – when in doubt, consult a doctor.